The National Center for Supercomputing Applications (NCSA) is a state-federal partnership to develop and deploy national-scale computer infrastructure that advances research, science and engineering based in the United States. NCSA operates as a unit of the University of Illinois Urbana-Champaign, and provides high-performance computing resources to researchers across the country. Support for NCSA comes from the National Science Foundation, the state of Illinois, the University of Illinois, business and industry partners, and other federal agencies.

NCSA provides leading-edge computing, data storage, and visualization resources. NCSA computational and data environment implements a multi-architecture hardware strategy, deploying both clusters and shared memory systems to support high-end users and communities on the architectures best-suited to their requirements. Nearly 1,360 scientists, engineers and students used the computing and data systems at NCSA to support research in more than 830 projects.

NCSA is led by Bill Gropp.